Horizon Europe 2026-2027 Work Programme published

The European Commission has published the Horizon Europe Work Programme for 2026 and 2027, setting out the next wave of research and innovation funding under the EU’s flagship programme. The overall programme allocates €14 billion to strategic research and innovation priorities across multiple clusters, including health, digital, industry, climate and more.

Within Cluster 1 “Health”, several calls address key scientific challenges and emerging technologies. Among them, topics linked to Virtual Human Twins (VHTs) — advanced in-silico computational models representing human health and disease — feature prominently. These digital twin approaches aim to support integrated clinical decision support, personalised prevention, improved diagnostics, and tailored health solutions.

Examples of VHT-related research opportunities include:

  • Tools and Technologies supporting clinical decision-making through Virtual Human Twins (VHTs) for prevention and diagnosis (2027 call).

In addition, health topics such as predictive biomarkers using AI, personalised approaches to reduce risks from adverse drug reactions, and other digital health solutions are also included in the 2026–2027 calls, offering broad opportunities for the in silico medicine community.

Planning to apply?

The VPH team is happy to be involved in your applications in a supporting role, taking on tasks related to consortium building, stakeholder outreach, communication, dissemination, social sciences, regulatory science and policy.

Partner up with us